When you add multiple middlewares using either `@app.middleware()` decorator or `app.add_middleware()` method, each new middleware wraps the application, forming a stack. The last middleware added is the *outermost*, and the first is the *innermost*.

On the request path, the *outermost* middleware runs first.

On the response path, it runs last.

For example:

```Python
app.add_middleware(MiddlewareA)
app.add_middleware(MiddlewareB)
```